Abstract
Objective:
To report a patient with myalgia and cramps possibly induced by the antimigrainous agent zolmitriptan.
Case report:
A 27-year-old woman with episodes of common migraine developed cramps and generalized myalgia after the use of intranasal zolmitriptan 5 mg to treat 3 episodes of migraine. This side effect had not occurred with oral zolmitriptan 2.5 mg.
Conclusion:
Myalgia and cramps should be considered a possible dose-dependent adverse effect of zolmitriptan.
MeSH terms
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Administration, Intranasal
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Administration, Oral
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Adult
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Humans
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Male
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Migraine Disorders / complications
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Migraine Disorders / drug therapy
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Muscle Cramp / chemically induced*
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Muscular Diseases / chemically induced*
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Oxazolidinones / administration & dosage
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Oxazolidinones / adverse effects*
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Oxazolidinones / therapeutic use
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Pain / chemically induced
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Serotonin Receptor Agonists / administration & dosage
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Serotonin Receptor Agonists / adverse effects*
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Serotonin Receptor Agonists / therapeutic use
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Tryptamines / administration & dosage
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Tryptamines / adverse effects*
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Tryptamines / therapeutic use
Substances
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Oxazolidinones
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Serotonin Receptor Agonists
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Tryptamines
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zolmitriptan