Myalgia and cramps associated with zolmitriptan

Clin Neuropharmacol. 2005 Sep-Oct;28(5):241-2. doi: 10.1097/01.wnf.0000183448.66152.25.

Abstract

Objective: To report a patient with myalgia and cramps possibly induced by the antimigrainous agent zolmitriptan.

Case report: A 27-year-old woman with episodes of common migraine developed cramps and generalized myalgia after the use of intranasal zolmitriptan 5 mg to treat 3 episodes of migraine. This side effect had not occurred with oral zolmitriptan 2.5 mg.

Conclusion: Myalgia and cramps should be considered a possible dose-dependent adverse effect of zolmitriptan.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intranasal
  • Administration, Oral
  • Adult
  • Humans
  • Male
  • Migraine Disorders / complications
  • Migraine Disorders / drug therapy
  • Muscle Cramp / chemically induced*
  • Muscular Diseases / chemically induced*
  • Oxazolidinones / administration & dosage
  • Oxazolidinones / adverse effects*
  • Oxazolidinones / therapeutic use
  • Pain / chemically induced
  • Serotonin Receptor Agonists / administration & dosage
  • Serotonin Receptor Agonists / adverse effects*
  • Serotonin Receptor Agonists / therapeutic use
  • Tryptamines / administration & dosage
  • Tryptamines / adverse effects*
  • Tryptamines / therapeutic use

Substances

  • Oxazolidinones
  • Serotonin Receptor Agonists
  • Tryptamines
  • zolmitriptan