Effect of hinge location on corneal sensation and dry eye after laser in situ keratomileusis for myopia

J Cataract Refract Surg. 2005 Oct;31(10):1881-7. doi: 10.1016/j.jcrs.2005.03.074.

Abstract

Purpose: To evaluate the effects of a superior or nasal hinge location on corneal sensation and dry eye after laser in situ keratomileusis (LASIK).

Setting: Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.

Methods: This prospective randomized masked study included 47 patients having bilateral myopic LASIK surgery. The first eye was randomly assigned to have a nasal or superior hinge flap; the fellow eye had the alternate location. Visual acuity, contrast sensitivity, corneal sensation, basic secretion test, tear film breakup time, conjunctival and corneal staining, and a subjective questionnaire were evaluated preoperatively and postoperatively at 1 week and 1, 3, and 6 months. The Wilcoxon signed rank test and paired t test were used for comparison.

Results: Dry eye occurred with the same frequency in both groups. However, eyes with the nasal hinge had significantly better nasal sensation than those with the superior hinge (P<.05) at 1 month.

Conclusion: Better nasal corneal sensation was found at 1 month in the nasal hinge group but there was no difference in any other parameters measured.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Conjunctiva / pathology
  • Contrast Sensitivity
  • Cornea / innervation
  • Cornea / pathology
  • Cornea / physiopathology*
  • Dry Eye Syndromes / etiology*
  • Female
  • Humans
  • Keratomileusis, Laser In Situ / adverse effects*
  • Male
  • Middle Aged
  • Myopia / pathology
  • Myopia / physiopathology
  • Myopia / surgery*
  • Postoperative Period
  • Sensation*
  • Single-Blind Method
  • Staining and Labeling
  • Surgical Flaps / innervation*
  • Surveys and Questionnaires
  • Tears / metabolism
  • Time Factors