A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18485-90. doi: 10.1073/pnas.0509455102. Epub 2005 Dec 13.

Abstract

We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing gene data sets and evidence for the existence of approximately 24,000 previously undescribed genomic loci. The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing / genetics
  • Animals
  • Gene Expression Profiling*
  • Gene Expression Regulation, Developmental / genetics*
  • Mice / genetics*
  • Mice, Inbred C57BL / genetics*
  • Multigene Family / genetics
  • RNA, Untranslated / genetics
  • Reproducibility of Results
  • Transcription, Genetic / genetics

Substances

  • RNA, Untranslated