Bloodstream infections with metallo-beta-lactamase-producing Pseudomonas aeruginosa: epidemiology, microbiology, and clinical outcomes

Alexandre R Marra; Carlos Alberto P Pereira; Ana Cristina Gales; Liana C Menezes; Ruy Guilherme R Cal; José Marconi A de Souza; Michael B Edmond; Cynthia Faro; Sérgio B Wey

doi:10.1128/AAC.50.1.388-390.2006

Bloodstream infections with metallo-beta-lactamase-producing Pseudomonas aeruginosa: epidemiology, microbiology, and clinical outcomes

Antimicrob Agents Chemother. 2006 Jan;50(1):388-90. doi: 10.1128/AAC.50.1.388-390.2006.

Authors

Alexandre R Marra¹, Carlos Alberto P Pereira, Ana Cristina Gales, Liana C Menezes, Ruy Guilherme R Cal, José Marconi A de Souza, Michael B Edmond, Cynthia Faro, Sérgio B Wey

Affiliation

¹ Divsion of Infectious Diseases, Universidade Federal de São Paulo, Brasil (UNIFESP-EPM)/Hospital São Paulo, Escola Paulista de Medicina, Rua Napoleão de Barros, 715 7th andar, CEP 04023-062, São Paulo, SP, Brazil. a.marra@uol.com.br

Abstract

Pseudomonas aeruginosa strains that produce metallo-beta-lactamases (MBLs) are becoming increasingly prevalent. We evaluated the epidemiological and microbiological characteristics of monomicrobial bloodstream infections caused by MBL-producing P. aeruginosa isolates, as well as the clinical outcomes in patients with these infections.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteremia / drug therapy
Bacteremia / epidemiology
Bacteremia / microbiology
Humans
Pseudomonas Infections / drug therapy
Pseudomonas Infections / epidemiology
Pseudomonas Infections / microbiology*
Pseudomonas aeruginosa / drug effects
Pseudomonas aeruginosa / enzymology*
Treatment Outcome
beta-Lactamases / genetics
beta-Lactamases / metabolism*

Substances

beta-Lactamases