Calcium supplementation for 1 y does not reduce body weight or fat mass in young girls

Am J Clin Nutr. 2006 Jan;83(1):18-23. doi: 10.1093/ajcn/83.1.18.

Abstract

Background: Accumulating evidence from observational studies indicates that a high calcium intake may reduce body weight and body fat. However, few randomized trials have been conducted.

Objective: We examined whether calcium supplementation affects body weight and body fat in young girls and whether a relation exists between habitual calcium intake and body weight and body fat.

Design: A randomized, double-blind, placebo-controlled intervention study was conducted in 110 young girls. The subjects were randomly assigned to receive 500 mg Ca/d as calcium carbonate or placebo for 1 y. Two groups of girls were selected according to habitual calcium intake from a large group; one group consumed 1000-1304 mg/d (40th-60th percentile; n = 60) and the other group consumed <713 mg/d (<20th percentile; n = 50). Height, body weight, body fat, and calcium intake were measured at baseline and after 1 y.

Results: At baseline a significant negative correlation was observed between habitual dietary calcium intake and percentage of body fat (r = -0.242, P = 0.011). However, calcium supplementation had no effect on height, body weight, or percentage body fat.

Conclusions: Habitual dietary calcium intake was inversely associated with body fat, but a low-dose calcium supplement had no effect on body weight, height, or body fat over 1 y in young girls. It is possible that the effect of calcium on body weight is only exerted if it is ingested as part of a meal, or the effect may be due to other ingredients in dairy products, and calcium may simply be a marker for a high dairy intake.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / drug effects*
  • Adipose Tissue / metabolism
  • Adolescent
  • Body Composition / drug effects
  • Body Composition / physiology
  • Body Height / drug effects
  • Body Height / physiology
  • Body Weight / drug effects*
  • Calcium / administration & dosage*
  • Calcium / pharmacology
  • Calcium, Dietary / administration & dosage*
  • Calcium, Dietary / pharmacology
  • Dietary Supplements
  • Double-Blind Method
  • Feeding Behavior
  • Female
  • Humans
  • Linear Models
  • Vitamin D / analogs & derivatives
  • Vitamin D / blood

Substances

  • Calcium, Dietary
  • Vitamin D
  • 25-hydroxyvitamin D
  • Calcium