External correlates of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) Content Component Scales were identified using an inpatient sample of 544 adults. The Brief Psychiatric Rating Scale (BPRS) and Symptom Checklist 90-Revised (SCL-90-R) produced correlates of the Content Component Scales, demonstrating external validity with clinician-rated and self-report scales. Relationships between MMPI-2 Content Component Scales and patient hospital chart variables were also examined. Results demonstrated cross-criterion validity in that most MMPI-2 Content Component Scales correlated with appropriate BPRS dimensions, SCL-90-R items, and other patient variables. Discriminant validity of the Content Component Scales was also demonstrated. In addition, the finding that similar patterns of correlates are produced when the component scales are correlated with a self-report measure, as well as clinician ratings and medical chart variables, provides converging lines of evidence supporting the construct validity of the Content Component Scales.