Effects of heart transplantation on cerebral metabolic abnormalities in patients with congestive heart failure

J Heart Lung Transplant. 2006 Mar;25(3):353-5. doi: 10.1016/j.healun.2005.09.012. Epub 2005 Dec 9.

Abstract

We investigated the serial changes in cerebral metabolites in 34 patients with congestive heart failure before and 2 and 12 months after heart transplantation, using proton magnetic resonance spectroscopy. Regional differences were detected in the recovery of cerebral metabolites after the heart transplantation procedure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aspartic Acid / analogs & derivatives
  • Aspartic Acid / metabolism
  • Brain / metabolism*
  • Choline / metabolism
  • Creatine / metabolism
  • Female
  • Heart Failure / metabolism
  • Heart Failure / surgery*
  • Heart Transplantation / physiology*
  • Humans
  • Inositol / metabolism
  • Magnetic Resonance Spectroscopy
  • Male
  • Middle Aged
  • Occipital Lobe / metabolism
  • Parietal Lobe / metabolism

Substances

  • Aspartic Acid
  • Inositol
  • N-acetylaspartate
  • Creatine
  • Choline