Discovery of an imidazo-phenanthridine synthon produced in a 'five-step one-pot reaction' leading to a new family of heterocycles with novel physical properties

Chem Commun (Camb). 2006 Mar 21:(11):1194-6. doi: 10.1039/b517117b. Epub 2006 Jan 19.

Abstract

A new class of heterocyclic aromatic cation with novel physical properties has been constructed by an unprecedented reaction pathway that proceeds via five spontaneous steps to yield a 'synthon' that can be further derivatised by a final nucleophilic substitution step.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry
  • Heterocyclic Compounds* / chemical synthesis
  • Heterocyclic Compounds* / chemistry
  • Imidazoles* / chemical synthesis
  • Imidazoles* / chemistry
  • Models, Molecular
  • Molecular Structure
  • Phenanthridines* / chemical synthesis
  • Phenanthridines* / chemistry
  • Structure-Activity Relationship

Substances

  • Heterocyclic Compounds
  • Imidazoles
  • Phenanthridines
  • DNA