Absence of sexual dimorphism in the goat: Induction of luteinizing hormone discharge in the castrated male and female and in the intersex with estradiol benzoate

G D Dial; B S Wiseman; R S Ott; A L Smith; J E Hixon

doi:10.1016/0093-691x(85)90037-8

Absence of sexual dimorphism in the goat: Induction of luteinizing hormone discharge in the castrated male and female and in the intersex with estradiol benzoate

Theriogenology. 1985 Feb;23(2):351-60. doi: 10.1016/0093-691x(85)90037-8.

Authors

G D Dial¹, B S Wiseman, R S Ott, A L Smith, J E Hixon

Affiliation

¹ Department of Food Animal and Equine Medicine, School of Veterinary Medicine North Carolina State University, Raleigh, NC 27606 USA.

PMID: 16726004
DOI: 10.1016/0093-691x(85)90037-8

Abstract

Gonadectomized male (n = 5) and female (n = 5) and intact intersex goats (n = 2) were injected i.m. with 50 mug 17(beta)-estradiol benzoate (EB). After treatment, there was a transient 6- to 9-hr decrease in circulating levels of LH followed by a preovulatory-like discharge of LH in all goats. Release peaked at 12 to 18 hr after EB treatment. The magnitude of discharge and the time from treatment until peak of release were not influenced by the goat's sex. These findings suggested that the positive feedback effects of estrogen on LH release were not sexually differentiated in the goat. Since tonic concentrations of LH prior to EB treatment were not different among the groups, the studies also suggested that the intersex goats lacked the inhibitory gonadal influences on gonadotropin release that characterize intact animals.