A long-time, high spatiotemporal resolution optical recording system for membrane potential activity via real-time writing to the hard disk

J Physiol Sci. 2006 Jun;56(3):263-6. doi: 10.2170/physiolsci.TN003006. Epub 2006 May 27.

Abstract

Using real-time hard disk recording, we have developed an optical system for the long-duration detection of changes in membrane potential from 1,020 sites with a high temporal resolution. The signal-to-noise ratio was sufficient for analyzing the spreading pattern of excitatory waves in frog atria in a single sweep.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Atrial Function / physiology
  • Coloring Agents
  • Computer Systems*
  • Computers
  • Electronic Data Processing / instrumentation
  • Electronic Data Processing / methods*
  • Electrophysiology
  • Equipment Design
  • Heart Atria / innervation
  • Membrane Potentials / physiology*
  • Optics and Photonics*
  • Rana catesbeiana
  • Software

Substances

  • Coloring Agents