The management of borderline tumours of the ovary

Curr Opin Oncol. 2006 Sep;18(5):488-93. doi: 10.1097/01.cco.0000239889.98289.ce.

Abstract

Purpose of review: The treatment of borderline ovarian tumours has been similar to that for their invasive counterparts for a long time. However, in view of the good prognosis for borderline ovarian tumours, their occurrence in a younger age group and the development of less invasive techniques, the question can be asked as to whether a more conservative treatment is warranted.

Recent findings: Recent articles discuss the mode of surgery (laparotomy or laparoscopy), the possibility of fertility-sparing surgery, the need for restaging procedures and adjuvant therapy.

Summary: The ultimate goal in treating patients with borderline ovarian cancer is defining those patients with bad prognostic factors and risk for recurrence and who consequently require more aggressive therapy. A proper staging procedure is crucial to estimate the risk. Translational research might help identify borderline tumours with poor prognosis. Fertility-sparing surgery is often a good option in young patients with Fédération International de Gynécologie et Obstétrie (FIGO) stage I disease or in selected cases with noninvasive implants, since long-term survival does not seem to be negatively influenced by conservative surgery.

Publication types

  • Review

MeSH terms

  • Chemotherapy, Adjuvant
  • Female
  • Humans
  • Ovarian Neoplasms* / diagnosis
  • Ovarian Neoplasms* / surgery
  • Ovarian Neoplasms* / therapy
  • Prognosis