Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial

Ken B Waites; Lynn B Duffy; Michael J Dowzicky

doi:10.1128/AAC.00210-06

Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial

Antimicrob Agents Chemother. 2006 Oct;50(10):3479-84. doi: 10.1128/AAC.00210-06.

Authors

Ken B Waites¹, Lynn B Duffy, Michael J Dowzicky

Affiliation

¹ Section of Clinical Microbiology, University of Alabama at Birmingham, Birmingham, AL 35249, USA. waites@path.uab.edu

Abstract

The activities of tigecycline and comparators against isolates collected from 76 U.S. centers between January 2004 and September 2005 were assessed. Tigecycline MIC(90)s were < or =2 microg/ml for Klebsiella pneumoniae, Klebsiella oxytoca, Escherichia coli, Enterobacter aerogenes, Enterobacter cloacae, Serratia marcescens, Acinetobacter baumannii, Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, and Streptococcus agalactiae.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Drug Resistance, Bacterial*
Gram-Negative Bacteria / drug effects*
Gram-Negative Bacteria / isolation & purification
Gram-Positive Bacteria / drug effects*
Gram-Positive Bacteria / isolation & purification
Hospitalization*
Humans
Microbial Sensitivity Tests
Minocycline / analogs & derivatives*
Minocycline / pharmacology
Population Surveillance
Tigecycline
United States

Substances

Anti-Bacterial Agents
Tigecycline
Minocycline