Abstract
We report the first coupling of a desorption electrospray ionization (DESI) ion source to Fourier transform ion cyclotron resonance mass spectrometry (ESI-FT-ICR-MS) for high-resolution protein analysis. The DESI FT-ICR-MS source design is described in detail along with preliminary data obtained on peptides and proteins ranging from 1 to 5.7 kDa.
Copyright 2006 John Wiley & Sons, Ltd.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Bradykinin / analysis
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Formates / analysis
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Glucagon / analysis
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Insulin / analysis
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Melitten / analysis
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Peptides / analysis*
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Proteins / analysis*
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Spectrometry, Mass, Electrospray Ionization / methods*
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Spectroscopy, Fourier Transform Infrared*
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Vasodilator Agents / analysis
Substances
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Formates
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Insulin
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Peptides
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Proteins
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Vasodilator Agents
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formic acid
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Melitten
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Glucagon
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Bradykinin