[Radionuclide X-ray fluorescence as an alternative method to pharmacopeial tests for heavy metals]

Ceska Slov Farm. 2006 Sep;55(5):213-8.
[Article in Slovak]

Abstract

Pharmacopeial tests for heavy metals require comparisons between test solution's colour after addition of thioacetamide and a control solution containing a known quantity of Pb. As this test neither informs about the type of heavy metals, nor about the concentrations of each of them, there is a reason for more frequent employment of instrumental methods such as AAS and AES, as well as ICP, NAA, and X-ray fluorescence. These methods provide us with quick and exact elemental analyses of impurities, thus becoming more and more important in the quality control of drugs and medicinal plants.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Metals, Heavy / analysis*
  • Pharmaceutical Preparations / analysis*
  • Plant Preparations / analysis*
  • Spectrometry, X-Ray Emission*

Substances

  • Metals, Heavy
  • Pharmaceutical Preparations
  • Plant Preparations