Are abnormal fidgety movements an early marker for complex minor neurological dysfunction at puberty?

Early Hum Dev. 2007 Aug;83(8):521-5. doi: 10.1016/j.earlhumdev.2006.10.001. Epub 2006 Nov 28.

Abstract

Background: Prechtl's method on the qualitative assessment of general movements (GMs) is a powerful tool for early and specific prediction of cerebral palsy. However, it is uncertain whether the GM assessment can be used to predict mild neurological impairment.

Aims: To determine whether the quality of general movements (GMs) from the age of 3 to 5 months, i.e. fidgety movements, is related to the presence of complex minor neurological dysfunctions (MND) 13 to 15 years later.

Study design: Prospectively collected data on the quality of GMs during infancy were retrospectively analysed on the basis of MND at puberty.

Subjects: Twenty-eight participants (14 girls and 14 boys) with a median gestational age of 40 weeks (range: 35 to 42 weeks) and an appropriate birth weight (median 3390 g; range 1900 to 4200 g).

Outcome measures: Touwen's neurological examination.

Results and conclusions: Abnormal fidgety movements were not related to later complex MND, but to fine manipulative disabilities (p<0.05). Normal fidgety movements, which are continually present in the whole body, might be required for optimal calibration of the proprioceptive system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Biomarkers
  • Female
  • Humans
  • Infant
  • Male
  • Movement Disorders / physiopathology*
  • Nervous System Diseases / physiopathology*
  • Prospective Studies
  • Puberty*

Substances

  • Biomarkers