Structure of internalising symptoms in early adulthood

Br J Psychiatry. 2006 Dec:189:540-6. doi: 10.1192/bjp.bp.106.022384.

Abstract

Background: Debate surrounds the underlying structure of internalising disorders including major depression, generalised anxiety disorder, phobias and panic disorders.

Aims: To model the within-time and across-time relationships of internalising symptoms, incorporating effects from generalised internalising and disorder-specific components of continuity.

Method: Data were gathered from a 25-year longitudinal study of a birth cohort of 953 New Zealand children. Outcome measures included DSM-IV symptom scores for major depression, generalised anxiety disorder, phobia and panic disorder at the ages of 18, 21 and 25 years.

Results: Structural equation modelling showed that, within-times, a common underlying measure of generalised internalising explained symptom score comorbidities. Across-time correlation of symptom scores was primarily accounted for by continuity over time in generalised internalising. However, for major depression and phobia there was also evidence of across-time continuity in the disorder-specific components of symptoms.

Conclusions: Internalising symptoms can be partitioned into components reflecting both a generalised tendency to internalising and disorder-specific components.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / psychology*
  • Child
  • Child, Preschool
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Internal-External Control*
  • Longitudinal Studies
  • Male
  • Models, Psychological
  • New Zealand