Treatment of recurrent pulmonary vein stenoses with endovascular stenting and adjuvant oral sirolimus

Catheter Cardiovasc Interv. 2007 Feb 15;69(3):362-8. doi: 10.1002/ccd.21036.

Abstract

The increasing use of radiofrequency catheter ablation for the cure of atrial fibrillation has led to iatrogenic pulmonary vein stenosis as a new clinical entity. The optimal diagnostic modality and treatment for pulmonary vein stenosis and restenosis remain unclear. We report the successful treatment of pulmonary vein restenosis following percutaneous balloon angioplasty, and for the first time, following surgical bovine pericardial patch angioplasty, with endovascular stenting and adjuvant oral sirolimus. Both patients remain asymptomatic at 1 year follow-up without evidence of restenosis.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Angioplasty, Balloon
  • Atrial Fibrillation / surgery
  • Blood Vessel Prosthesis Implantation
  • Catheter Ablation / adverse effects
  • Echocardiography, Transesophageal
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Middle Aged
  • Pulmonary Veno-Occlusive Disease / etiology
  • Pulmonary Veno-Occlusive Disease / therapy*
  • Recurrence
  • Sirolimus / therapeutic use*
  • Stents*
  • Ultrasonography, Doppler, Color

Substances

  • Immunosuppressive Agents
  • Sirolimus