Continuous subcutaneous infusion of hyoscine butylbromide reduces secretions in patients with gastrointestinal obstruction

J Pain Symptom Manage. 1991 Nov;6(8):484-6. doi: 10.1016/0885-3924(91)90005-o.

Abstract

We describe the use of hyoscine butylbromide as a subcutaneous infusion in 3 patients with inoperable malignant bowel obstruction. An objective reduction of drainage from the gastrointestinal tract was observed with the hyoscine butylbromide infusion (60-120 mg/day). We suggest that this effect can be useful in the palliative treatment of vomiting in inoperable bowel obstruction.

MeSH terms

  • Aged
  • Butylscopolammonium Bromide / administration & dosage*
  • Butylscopolammonium Bromide / pharmacology
  • Drainage
  • Female
  • Genital Neoplasms, Female / complications
  • Humans
  • Injections, Subcutaneous
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / therapy*
  • Intestinal Secretions / drug effects*
  • Intubation, Gastrointestinal
  • Middle Aged
  • Palliative Care*

Substances

  • Butylscopolammonium Bromide