Abstract
Symmetric non-erosive polyarthritis is the most common clinical feature in systemic lupus erythematosus (SLE). We report on a 42-year follow-up of a 71-year-old woman who first had polyarthritis in 1963 at the age of 29 and continuously since 1975. SLE was diagnosed in 2000 at the age of 66 as anti-dsDNA (56 kIU/l), and antinuclear antibodies (1:2,560) turned positive. In 2005 hand and feet radiographs revealed severe Jaccoud's arthritis with subluxations but without erosions.
MeSH terms
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Age of Onset
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Aged
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Antibodies, Antinuclear / analysis
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Antibodies, Antinuclear / blood
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Antibodies, Antinuclear / immunology
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Arthritis / diagnosis*
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Arthritis / immunology*
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Arthritis / physiopathology
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Arthrography
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Autoantibodies / analysis
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DNA / immunology
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Disease Progression
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Female
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Finland
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Foot / diagnostic imaging
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Foot / pathology
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Hand / diagnostic imaging
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Hand / pathology
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Humans
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Joints / immunology*
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Joints / pathology*
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Joints / physiopathology
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Lupus Erythematosus, Systemic / complications*
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Lupus Erythematosus, Systemic / immunology*
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Lupus Erythematosus, Systemic / physiopathology
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Serotyping
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Time Factors
Substances
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Antibodies, Antinuclear
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Autoantibodies
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DNA