Use of molecular epidemiology to confirm a multistate outbreak of hepatitis A caused by consumption of oysters

Stephanie R Bialek; Prethiba A George; Guo-Liang Xia; Marc B Glatzer; Miles L Motes; John E Veazey; Roberta M Hammond; Timothy Jones; Y Carol Shieh; Janet Wamnes; Gilberto Vaughan; Yury Khudyakov; Anthony E Fiore

doi:10.1086/511874

Use of molecular epidemiology to confirm a multistate outbreak of hepatitis A caused by consumption of oysters

Clin Infect Dis. 2007 Mar 15;44(6):838-40. doi: 10.1086/511874. Epub 2007 Feb 13.

Authors

Stephanie R Bialek¹, Prethiba A George, Guo-Liang Xia, Marc B Glatzer, Miles L Motes, John E Veazey, Roberta M Hammond, Timothy Jones, Y Carol Shieh, Janet Wamnes, Gilberto Vaughan, Yury Khudyakov, Anthony E Fiore

Affiliation

¹ Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. sbialek@cdc.gov

PMID: 17304457
DOI: 10.1086/511874

Abstract

The 39 oyster consumption-related cases of hepatitis A reported in 2005 represent the first large outbreak of hepatitis A associated with shellfish consumption in the United States in >15 years. This is the first outbreak investigation in which an identical hepatitis A virus sequence was obtained from both the implicated food product and case patients.

MeSH terms

Adolescent
Adult
Age Distribution
Aged
Animals
Case-Control Studies
Confidence Intervals
Disease Outbreaks*
Female
Food Contamination / analysis
Food Contamination / statistics & numerical data*
Hepatitis A / diagnosis
Hepatitis A / epidemiology*
Hepatitis A / virology
Hepatitis A virus / genetics
Hepatitis A virus / isolation & purification*
Humans
Incidence
Male
Middle Aged
Molecular Epidemiology
Odds Ratio
Ostreidae / virology*
Polymerase Chain Reaction
RNA, Viral / analysis
Risk Assessment
Sex Distribution

Substances

RNA, Viral