Low serum concentrations of reboxetine in 2 patients treated with CYP3A4 inducers

J Clin Psychopharmacol. 2007 Jun;27(3):308-10. doi: 10.1097/01.jcp.0000270089.47533.b0.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adrenergic Uptake Inhibitors / administration & dosage
  • Adrenergic Uptake Inhibitors / blood*
  • Adrenergic Uptake Inhibitors / therapeutic use
  • Adult
  • Anticonvulsants / pharmacology*
  • Anticonvulsants / therapeutic use
  • Bulimia Nervosa / drug therapy
  • Carbamazepine / pharmacology
  • Carbamazepine / therapeutic use
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System / biosynthesis*
  • Drug Antagonism
  • Enzyme Induction
  • Female
  • Humans
  • Male
  • Middle Aged
  • Morpholines / administration & dosage
  • Morpholines / blood*
  • Morpholines / therapeutic use
  • Phenobarbital / pharmacology
  • Phenobarbital / therapeutic use
  • Reboxetine
  • Schizophrenia / drug therapy

Substances

  • Adrenergic Uptake Inhibitors
  • Anticonvulsants
  • Morpholines
  • Carbamazepine
  • Cytochrome P-450 Enzyme System
  • Reboxetine
  • Cytochrome P-450 CYP3A
  • CYP3A4 protein, human
  • Phenobarbital