Aminophylline in bradyasystolic cardiac arrest

Emerg Med J. 2007 Aug;24(8):582-3. doi: 10.1136/emj.2007.051342.

Abstract

A short cut review was carried out to establish whether aminophylline improved return of spontaneous circulation rates and eventual outcome in bradyasystolic cardiac arrest. A total of 1154 papers were found using the reported searches, of which four presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these four papers are summarised in table 4. It is concluded that aminophylline offers no benefit in this situation.

Publication types

  • Review

MeSH terms

  • Adenosine / antagonists & inhibitors
  • Adult
  • Aminophylline / therapeutic use*
  • Bradycardia / drug therapy*
  • Cardiotonic Agents / therapeutic use*
  • Heart Arrest / drug therapy*
  • Humans
  • Systole / drug effects
  • Treatment Outcome

Substances

  • Cardiotonic Agents
  • Aminophylline
  • Adenosine