Cutaneous response to ultraviolet radiation-induced erythema in patients with type A dysplastic nevi

Photodermatol Photoimmunol Photomed. 1991 Feb;8(1):7-11.

Abstract

The effects of an exposure to 6 times the minimal erythemal dose of ultraviolet radiation (UV) were studied using a visual scale and a tri-stimulus colorimeter in 12 sun-tolerant (skin types III and IV) patients with type A dysplastic nevus syndrome. In such individuals, the melanocytic system would be susceptible to neoplastic transformation induced by sunlight. The cutaneous response to a marked UVB erythema has been shown to identify the high-risk patients prone to light-induced skin cancer. This study indicates that the UVB cutaneous susceptibility of patients with type A dysplastic nevi is not significantly different from control subjects, in terms of erythemal and tanning response.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Color
  • Colorimetry / methods
  • Disease Susceptibility
  • Dysplastic Nevus Syndrome / classification
  • Dysplastic Nevus Syndrome / physiopathology*
  • Erythema / pathology
  • Erythema / physiopathology*
  • Female
  • Humans
  • Male
  • Melanoma / physiopathology
  • Skin / pathology
  • Skin / radiation effects*
  • Skin Neoplasms / physiopathology*
  • Skin Pigmentation / radiation effects*
  • Ultraviolet Rays*