Geminal bismethylation prevents polyketide oxidation and dimerization in the benastatin pathway

Angew Chem Int Ed Engl. 2007;46(37):7035-8. doi: 10.1002/anie.200702033.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / metabolism
  • Dimerization
  • Glutathione Transferase / antagonists & inhibitors
  • Macrolides / chemistry*
  • Methylation
  • Molecular Structure
  • Naphthacenes* / chemistry
  • Naphthacenes* / metabolism
  • Oxidation-Reduction
  • Streptomyces lividans / chemistry

Substances

  • Antineoplastic Agents
  • Macrolides
  • Naphthacenes
  • benastatin A
  • Glutathione Transferase