Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome

Pediatr Emerg Care. 2007 Sep;23(9):659-61. doi: 10.1097/PEC.0b013e31814b2ddd.

Abstract

Malignant hypertension due to autonomic dysfunction is a known complication of Guillain-Barré syndrome. We describe a child who presented with status epilepticus secondary to hypertensive encephalopathy who, in recovery, was found to be areflexic. Nerve conduction studies confirmed the clinical diagnosis of Guillain-Barré syndrome. She was treated with antihypertensive and antiseizure medications and intravenous immune globulin with complete resolution of her autonomic symptoms and improvement in her weakness. Guillain-Barré syndrome may result in hypertensive encephalopathy that can manifest as status epilepticus before the onset of motor symptoms.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Amines / therapeutic use
  • Anticonvulsants / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Cyclohexanecarboxylic Acids / therapeutic use
  • Diagnosis, Differential
  • Electroencephalography
  • Female
  • Gabapentin
  • Guillain-Barre Syndrome / diagnosis*
  • Humans
  • Hypertensive Encephalopathy / diagnosis*
  • Hypertensive Encephalopathy / drug therapy
  • Immunoglobulins / therapeutic use
  • Labetalol / therapeutic use
  • Phenytoin / therapeutic use
  • Spinal Puncture
  • Status Epilepticus / diagnosis*
  • Status Epilepticus / drug therapy
  • Tomography, X-Ray Computed
  • gamma-Aminobutyric Acid / therapeutic use

Substances

  • Amines
  • Anticonvulsants
  • Antihypertensive Agents
  • Cyclohexanecarboxylic Acids
  • Immunoglobulins
  • gamma-Aminobutyric Acid
  • Phenytoin
  • Gabapentin
  • Labetalol