Gastroparesis: symptoms, evaluation, and treatment

Gastroenterol Clin North Am. 2007 Sep;36(3):619-47, ix. doi: 10.1016/j.gtc.2007.07.004.

Abstract

Gastroparesis presents with gastrointestinal symptoms and nongastrointestinal manifestations in association with objective delays in gastric emptying. The condition may complicate several systemic disorders or may be idiopathic in nature. The diagnosis is made by directed evaluation to exclude organic diseases, which can mimic the clinical presentation of gastroparesis coupled with quantification of gastric emptying. Current therapies rely on dietary modifications, medications to stimulate gastric evacuation, and agents to reduce vomiting. Endoscopic and surgical options are increasingly used for cases refractory to medication treatment.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antiemetics / therapeutic use*
  • Diabetes Complications / complications*
  • Diabetes Complications / physiopathology
  • Diagnostic Imaging / methods*
  • Electric Stimulation Therapy / methods*
  • Endoscopy, Gastrointestinal / methods*
  • Gastrectomy / methods*
  • Gastric Bypass / adverse effects
  • Gastric Emptying
  • Gastroparesis* / diagnosis
  • Gastroparesis* / etiology
  • Gastroparesis* / therapy
  • Humans
  • Prognosis
  • Vagotomy, Proximal Gastric / adverse effects

Substances

  • Antiemetics