Depression, social support and adherence to highly active antiretroviral therapy in people living with HIV/AIDS

Sex Health. 2007 Dec;4(4):227-32. doi: 10.1071/sh06062.

Abstract

Background: The present study investigated the prevalence of depression in HIV-positive individuals and its association with adherence to highly active antiretroviral therapy (HAART).

Methods: HIV-positive (n = 80) and HIV-negative (n = 20) participants were assessed for depression and adherence via clinical interview and self-reporting.

Results: Fourteen percent of the HIV-seropositive group met the criteria for current mood disorder compared with 5% of controls. Similarly, 39% of the HIV-seropositive participants met the criteria for a past major depressive episode compared with 15% of controls. Non-adherence to HAART was reported by 30.5% of those prescribed HAART and was significantly associated with living alone and relationship status.

Conclusions: The present study found compromised psychological health in people living with HIV infection. It is recommended that health professionals continue to screen for depression, relationship status and living situation to ensure adherence to HAART.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Acquired Immunodeficiency Syndrome / drug therapy
  • Adult
  • Antiretroviral Therapy, Highly Active / psychology*
  • Depression / etiology*
  • Female
  • HIV Seropositivity / complications*
  • HIV Seropositivity / drug therapy
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Male
  • Middle Aged
  • Patient Compliance / psychology*
  • Regression Analysis
  • Social Support*
  • Surveys and Questionnaires
  • Victoria