An examination technique adapted to comply with the demands of CT colonography is not only a basic requirement for a high-quality examination and correct ascertainment of the findings; it is also essential for far-reaching applications of this method of examination. The technique of CT colonography is based on good patient preparation with the aid of fecal tagging, adequate distension of the colon with CO(2) and acquisition of data with the patient both prone and supine in a thin-slice technique using a low-dose protocol. The different technical aspects of CT colonography are explained in this paper.