Identifying patients with benign prostatic hyperplasia through a diagnosis of, or treatment for, erectile dysfunction

Curr Med Res Opin. 2008 Mar;24(3):775-84. doi: 10.1185/030079908X260916. Epub 2008 Jan 30.

Abstract

Objective: Erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) associated with benign prostate hyperplasia (BPH) are highly correlated. This study examined rates of screening, diagnosis, and treatment of BPH/LUTS among men seeking care for ED.

Research design and methods: This was a retrospective US claims data analysis (1999-2004) evaluating men > or = 40 years old with a new diagnosis of or prescription medication for ED. Multivariate analyses were used to examine times to screening, diagnosis, and treatment.

Results: 81 659 men with ED were identified (mean age 57 years). The baseline prevalence of recorded BPH was 1.5%. During the follow-up period (mean 2.2 years), 7.6% had documented BPH. Time to screening was shorter among patients seeing urologists (121.1 days) compared with those seeing primary-care physicians (282.2 days). Controlling for demographic and clinical characteristics, patients who saw a urologist were more likely to be screened (OR: 2.4, p < 0.0001), diagnosed with BPH (OR: 1.8, p < 0.0001), and treated (OR: 1.3, p < 0.0001), relative to patients seeing other providers. Men aged 75 and over were 43% less likely to be screened (p < 0.0001), but 5.4 times more likely to be diagnosed with BPH (p < 0.0001) and 5.3 times more likely to be treated (p < 0.0001) compared with men aged 40-49.

Conclusions: Screening for BPH appears less likely for men with ED who do not see a urologist. When screening does occur, it takes much longer with non-specialty providers. Patient age and provider specialty are key factors associated with screening, diagnosis, and treatment of BPH among men with ED.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic alpha-Antagonists / therapeutic use
  • Adult
  • Aged
  • Erectile Dysfunction / diagnosis*
  • Erectile Dysfunction / drug therapy*
  • Humans
  • Incidence
  • Insurance Claim Review
  • Male
  • Mass Screening
  • Middle Aged
  • Multivariate Analysis
  • Prevalence
  • Prostatic Hyperplasia / diagnosis*
  • Prostatic Hyperplasia / drug therapy
  • Prostatic Hyperplasia / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • United States / epidemiology
  • Urination Disorders / diagnosis*
  • Urination Disorders / drug therapy

Substances

  • Adrenergic alpha-Antagonists