Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes

Genome Biol. 2008;9(2):R34. doi: 10.1186/gb-2008-9-2-r34. Epub 2008 Feb 15.

Abstract

Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora http://ancora.genereg.net, a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory elements and domains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Databases, Genetic
  • Gene Expression Regulation, Developmental
  • Genes, Developmental*
  • Genes, Regulator*
  • Genome
  • Humans
  • Internet
  • Sequence Analysis, DNA / methods*
  • Software*
  • Untranslated Regions / genetics*

Substances

  • Untranslated Regions