Abstract
The incidence of invasive group A streptococcal disease has increased in Norway since the 1980s. Analysis of 100 isolates recovered from 1988 to 2003 showed an increased genotypic diversity over time, while the prevalence of the strain that dominated in 1988, sequence type (ST)-28/emm-1, decreased. Necrotizing fasciitis was often associated with ST-15/emm-3.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / pharmacology
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Antigens, Bacterial* / classification
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Antigens, Bacterial* / genetics
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Bacterial Outer Membrane Proteins* / classification
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Bacterial Outer Membrane Proteins* / genetics
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Carrier Proteins* / classification
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Carrier Proteins* / genetics
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Child
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Child, Preschool
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Fasciitis, Necrotizing / epidemiology
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Fasciitis, Necrotizing / microbiology
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Female
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Genetic Variation*
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Genotype
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Humans
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Incidence
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Infant
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Male
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Microbial Sensitivity Tests
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Middle Aged
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Norway / epidemiology
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Sequence Analysis, DNA* / methods
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Streptococcal Infections / epidemiology*
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Streptococcal Infections / microbiology
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Streptococcus pyogenes / classification*
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Streptococcus pyogenes / drug effects
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Streptococcus pyogenes / genetics*
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Streptococcus pyogenes / isolation & purification
Substances
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Anti-Bacterial Agents
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Antigens, Bacterial
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Bacterial Outer Membrane Proteins
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Carrier Proteins
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streptococcal M protein