Risk factors for osteoporosis and bone status in postmenopausal women with psoriasis treated with UVB therapy

Acta Derm Venereol. 2008;88(3):240-6. doi: 10.2340/00015555-0403.

Abstract

The aims of this study were to examine whether postmenopausal women with psoriasis who were exposed to regular ultraviolet light B (UVB) therapy had greater bone mineral density than women of similar age from the same region, and to estimate the influence of risk factors on bone status. A total of 35 randomly selected women, age (mean +/- SD) 69.3 +/- 6.29 years (age range 60-82 years), with active psoriasis, mean onset at 37.0 years (+/- 23.5 SD) were studied. The patients had been previously exposed to broadband or narrowband UVB. Age-matched, women (n = 2448) from Göteborg, examined at the Geriatric out-patient clinic during the years 2001 and 2002, were used as controls. Bone mineral density was examined by Dual-Energy X-ray Absorptiometry (Hologic Delphi A) at the hip and the lumbar spine. Medical history and lifestyle factors were assessed with a questionnaire. Postmenopausal women with psoriasis were found to have higher bone mineral density than age-matched controls. Higher body weight, physical activity and UVB exposure could explain this finding.

MeSH terms

  • Absorptiometry, Photon
  • Aged
  • Aged, 80 and over
  • Body Weight
  • Bone Density*
  • Case-Control Studies
  • Diet
  • Female
  • Fractures, Bone / epidemiology
  • Hormone Replacement Therapy
  • Humans
  • Hypothyroidism / epidemiology
  • Hypothyroidism / therapy
  • Middle Aged
  • Motor Activity
  • Osteoporosis, Postmenopausal / epidemiology*
  • Parity
  • Postmenopause*
  • Pregnancy
  • Psoriasis / epidemiology
  • Psoriasis / therapy*
  • Risk Factors
  • Sunlight
  • Sweden / epidemiology
  • Ultraviolet Therapy*