The three nucleotide deletion within the 3'untranslated region of MLH1 resulting in gene expression reduction is not a causal alteration in Lynch syndrome

Fam Cancer. 2008;7(4):339-40. doi: 10.1007/s10689-008-9196-6. Epub 2008 May 22.

Authors

J Tinat¹, S Baert-Desurmont, J B Latouche, S Vasseur, C Martin, E Bouvignies, T Frébourg

Affiliation

¹ Inserm U614, Faculty of Medicine and Department of Genetics, University Hospital, Institute for Biomedical Research, 22 Boulevard Gambetta, 76183, Rouen, France.

PMID: 18496770
DOI: 10.1007/s10689-008-9196-6

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

3' Untranslated Regions*
Adaptor Proteins, Signal Transducing / genetics*
Adult
Colorectal Neoplasms, Hereditary Nonpolyposis / genetics*
Gene Expression
Humans
Middle Aged
MutL Protein Homolog 1
Nuclear Proteins / genetics*
Sequence Deletion*

Substances

3' Untranslated Regions
Adaptor Proteins, Signal Transducing
MLH1 protein, human
Nuclear Proteins
MutL Protein Homolog 1