Abstract
Studies of depression and hippocampal volume have yielded inconsistent results. This inconsistency could stem from the heterogeneity of depressive disorders. We conducted cross-sectional and longitudinal analyses of hippocampal volumes in atypical depressive, melancholic depressive, and control subjects. We found no effect of depression subtype on hippocampal volume or memory performance.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Aged
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Atrophy
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Cross-Sectional Studies
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Depressive Disorder / classification
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Depressive Disorder / diagnosis*
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Depressive Disorder / psychology
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Diagnostic and Statistical Manual of Mental Disorders
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Dominance, Cerebral / physiology
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Female
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Hippocampus / pathology*
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Humans
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Image Processing, Computer-Assisted*
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Longitudinal Studies
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Magnetic Resonance Imaging*
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Male
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Middle Aged
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Neuropsychological Tests