Abstract
A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands is reported.
MeSH terms
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Chemistry, Pharmaceutical / methods
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Drug Design
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Humans
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Indoles / chemistry*
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Inhibitory Concentration 50
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Kinetics
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Ligands
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Models, Chemical
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Molecular Structure
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Protein Binding / drug effects
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Receptors, Serotonin / chemistry*
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Receptors, Serotonin / metabolism
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Stereoisomerism
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Structure-Activity Relationship
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Tryptamines / chemistry
Substances
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Indoles
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Ligands
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Receptors, Serotonin
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Tryptamines
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serotonin 6 receptor