Inhibition of protein kinase A improves effector function of monocytes from HIV-infected patients

AIDS Res Hum Retroviruses. 2008 Jul;24(7):1013-5. doi: 10.1089/aid.2008.0071.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 1-Methyl-3-isobutylxanthine / pharmacology
  • Adult
  • Anti-HIV Agents / therapeutic use
  • Antiretroviral Therapy, Highly Active
  • Cells, Cultured
  • Cyclic AMP-Dependent Protein Kinases / antagonists & inhibitors*
  • Cyclic Nucleotide Phosphodiesterases, Type 4 / metabolism
  • Dinoprostone / pharmacology*
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / immunology*
  • HIV*
  • Humans
  • Lipopolysaccharides / pharmacology
  • Male
  • Middle Aged
  • Monocytes / drug effects*
  • Monocytes / metabolism*
  • Phosphodiesterase Inhibitors / pharmacology
  • Rolipram / pharmacology
  • Tumor Necrosis Factor-alpha / biosynthesis*

Substances

  • Anti-HIV Agents
  • Lipopolysaccharides
  • Phosphodiesterase Inhibitors
  • Tumor Necrosis Factor-alpha
  • Cyclic AMP-Dependent Protein Kinases
  • Cyclic Nucleotide Phosphodiesterases, Type 4
  • PDE4B protein, human
  • Rolipram
  • Dinoprostone
  • 1-Methyl-3-isobutylxanthine