New antibacterial pentacyclic triterpenes from Myricaria elegans Royle. (tamariscineae)

J Enzyme Inhib Med Chem. 2008 Dec;23(6):1023-7. doi: 10.1080/14756360701841657.

Abstract

Two new pentacyclic triterpenes eleganene-A (1) and eleganene-B (2), along with four known pentacyclic triterpenes betulin (3), ursolic acid (4), erythrodiol (5) and corosolic acid (6) were isolated from the aerial parts of Myricaria elegans. These compounds exhibited significant antibacterial activity. The structure of compounds 1 and 2 were deduced on the basis of their spectral analysis.

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology*
  • Magnetic Resonance Spectroscopy
  • Microbial Viability / drug effects
  • Molecular Structure
  • Pentacyclic Triterpenes / chemistry*
  • Pentacyclic Triterpenes / pharmacology*
  • Structure-Activity Relationship
  • Tamaricaceae / chemistry*

Substances

  • Anti-Bacterial Agents
  • Pentacyclic Triterpenes