Corticosteroid treatment of behaviour, language and motor regression in childhood disintegrative disorder

Eur J Paediatr Neurol. 2009 Jul;13(4):367-9. doi: 10.1016/j.ejpn.2008.06.001. Epub 2008 Jul 14.

Abstract

Childhood disintegrative disorder (CDD) (ICD-10 F84.3) is defined by a period of normal development before onset followed by gradual loss of previously acquired skills with the development of characteristic abnormalities of social, communicative and behavioural functioning. We report two children with apparent CDD, who showed amelioration of behaviour, language and motor regression after corticosteroid treatment.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Child Development Disorders, Pervasive / complications
  • Child Development Disorders, Pervasive / drug therapy*
  • Child Development Disorders, Pervasive / psychology*
  • Child, Preschool
  • Developmental Disabilities / drug therapy*
  • Developmental Disabilities / etiology
  • Female
  • Humans
  • Language Development Disorders / drug therapy*
  • Language Development Disorders / etiology
  • Language*
  • Male
  • Movement Disorders / drug therapy*
  • Movement Disorders / etiology
  • Severity of Illness Index

Substances

  • Adrenal Cortex Hormones