Gender and other psychosocial factors as predictors of adherence to highly active antiretroviral therapy (HAART) in adults with comorbid HIV/AIDS, psychiatric and substance-related disorder

Allison J Applebaum; Mark A Richardson; Stephen M Brady; Deborah J Brief; Terence M Keane

doi:10.1007/s10461-008-9441-x

Gender and other psychosocial factors as predictors of adherence to highly active antiretroviral therapy (HAART) in adults with comorbid HIV/AIDS, psychiatric and substance-related disorder

AIDS Behav. 2009 Feb;13(1):60-5. doi: 10.1007/s10461-008-9441-x. Epub 2008 Aug 9.

Authors

Allison J Applebaum¹, Mark A Richardson, Stephen M Brady, Deborah J Brief, Terence M Keane

Affiliation

¹ Department of Psychology, Boston University, 648 Beacon Street, 2nd Floor, Boston, MA, 02215, USA. aja231@bu.edu

PMID: 18690532
DOI: 10.1007/s10461-008-9441-x

Abstract

This study assessed adherence to HAART among 67 HIV-infected adults, and the degree to which gender and psychological factors-including depression, drug and alcohol use, quality of life, and medication side effects-influenced adherence. Although overall adherence was greater than rates reported in similar studies, no significant difference in adherence was observed between men and women in the present sample. Medication side effects were a significant predictor of non-adherence in the sample at large and among women in particular, while alcohol dependence was a significant predictor of non-adherence only in women. Possible explanations are explored.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adult
Antiretroviral Therapy, Highly Active / psychology*
Chi-Square Distribution
Female
HIV Infections / drug therapy*
HIV Infections / epidemiology
HIV Infections / psychology
Humans
Longitudinal Studies
Male
Medication Adherence / psychology*
Psychology
Regression Analysis
Sex Factors
Socioeconomic Factors
Substance-Related Disorders / epidemiology
Substance-Related Disorders / psychology*