Abstract
Variation in the monoamine-oxidase-A (MAO-A) gene has been associated with volumetric changes in corticolimbic regions with differences in their response to relevant emotional tasks. Here we show no changes in baseline regional brain metabolism as a function of genotype indicating that, unchallenged, corticolimbic activity is not modulated by the MAO-A genotype.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adult
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Brain / anatomy & histology*
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Brain / metabolism*
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Cerebral Cortex / metabolism
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Genotype*
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Glucose / metabolism*
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Humans
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Limbic System / metabolism
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Male
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Monoamine Oxidase / genetics*
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Positron-Emission Tomography
Substances
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Monoamine Oxidase
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Glucose