Human herpesvirus 6 meningoradiculitis treated with intravenous immunoglobulin and valganciclovir

J Neurovirol. 2009 Jan;15(1):108-9. doi: 10.1080/13550280802385513. Epub 2008 Sep 23.

Abstract

Human herpesvirus 6 (HHV-6) is being increasingly associated with multiple neurological conditions. The authors report the case of a 26-year-old man with subacute meningoradiculitis initially treated with intravenous immunoglobulin. The cerebrospinal fluid (CSF) showed pleocytosis and polymerase chain reaction (PCR) was positive for HHV-6 type B DNA in the CSF and peripheral blood. He was subsequently treated with valganciclovir with near resolution of his symptoms.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use*
  • DNA, Viral / blood
  • DNA, Viral / cerebrospinal fluid
  • Ganciclovir / analogs & derivatives*
  • Ganciclovir / therapeutic use
  • Herpesvirus 6, Human*
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use*
  • Leukocytosis / cerebrospinal fluid
  • Male
  • Meningitis / therapy*
  • Meningitis / virology
  • Polymerase Chain Reaction
  • Radiculopathy / therapy*
  • Radiculopathy / virology
  • Roseolovirus Infections / complications
  • Roseolovirus Infections / therapy*
  • Treatment Outcome
  • Valganciclovir

Substances

  • Antiviral Agents
  • DNA, Viral
  • Immunoglobulins, Intravenous
  • Valganciclovir
  • Ganciclovir