Developing DNA tiles for oligonucleotide hybridization assay with higher accuracy and efficiency

Chem Commun (Camb). 2008 Nov 21:(43):5622-4. doi: 10.1039/b811332g. Epub 2008 Sep 29.

Abstract

We demonstrate the versatility of a DNA tile system for oligonucleotide hybridization assay and explored the detection limit of the probe tiles for DNA targets of varied lengths.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • DNA / chemistry*
  • DNA / ultrastructure
  • Nucleic Acid Hybridization / methods*
  • Oligonucleotide Probes / chemistry*
  • Particle Size
  • Sensitivity and Specificity

Substances

  • Oligonucleotide Probes
  • DNA