Reciprocal cellular and humoral immune responses in bovine tuberculosis

V Ritacco; B López; I N De Kantor; L Barrera; F Errico; A Nader

doi:10.1016/0034-5288(91)90143-c

Reciprocal cellular and humoral immune responses in bovine tuberculosis

Res Vet Sci. 1991 May;50(3):365-7. doi: 10.1016/0034-5288(91)90143-c.

Authors

V Ritacco¹, B López, I N De Kantor, L Barrera, F Errico, A Nader

Affiliation

¹ National University of Luján, Buenos Aires, Argentina.

PMID: 1909047
DOI: 10.1016/0034-5288(91)90143-c

Abstract

A sandwich ELISA for the detection of gamma interferon showed higher sensitivity and specificity than an indirect ELISA for mycobacterial antibodies in the diagnosis of bovine tuberculosis. Circumstantial evidence of an inverse relationship between cellular and humoral immune responses to Mycobacterium bovis was found in cattle with natural infection.

MeSH terms

Animals
Antibodies, Bacterial / biosynthesis*
Antibodies, Bacterial / blood
Cattle
Enzyme-Linked Immunosorbent Assay
Immunity, Cellular
Interferon-gamma / analysis*
Mycobacterium bovis / immunology*
Predictive Value of Tests
Tuberculin / immunology
Tuberculosis, Bovine / diagnosis
Tuberculosis, Bovine / immunology*

Substances

Antibodies, Bacterial
Tuberculin
Interferon-gamma