Abstract
Two sequential Suzuki coupling reactions have been developed for efficient synthesis of synthetically and biologically important 3,6-disubstituted 2,5-dioxybenzoquinone architectures in a highly chemoselective controlled manner. The method serves as a key step in the total synthesis of leucomelone in three steps and in 61% overall yield.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Benzoquinones / chemical synthesis*
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Benzoquinones / chemistry
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Boronic Acids / chemistry*
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Catalysis
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Catechols / chemical synthesis*
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Catechols / chemistry
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Combinatorial Chemistry Techniques
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Molecular Structure
Substances
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Benzoquinones
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Boronic Acids
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Catechols
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leucomelone