ESCRTing membrane deformation

Cell. 2009 Jan 9;136(1):15-7. doi: 10.1016/j.cell.2008.12.029.

Abstract

The ESCRT-III complex mediates membrane budding away from the cytosol in endosome biogenesis, cytokinesis, and viral budding. In this issue, Saksena et al. (2009) use an elegant fluorescence-based approach to define the sequential activation, recruitment, and disassembly of ESCRT-III subunits during membrane involution in vitro.

Publication types

  • Comment

MeSH terms

  • Cytosol / chemistry
  • Cytosol / metabolism
  • Endosomes / chemistry*
  • Endosomes / metabolism*
  • Humans
  • Spectrometry, Fluorescence
  • Vesicular Transport Proteins / chemistry*
  • Vesicular Transport Proteins / metabolism*
  • Yeasts

Substances

  • Vesicular Transport Proteins