Performance of OptiMAL-IT compared to microscopy, for malaria detection in Burkina Faso

Trop Med Int Health. 2009 Mar;14(3):338-40. doi: 10.1111/j.1365-3156.2009.02228.x. Epub 2009 Jan 28.

Abstract

Objective: To compare the performance of OptiMAL-IT, a rapid diagnostic test for malaria, with that of microscopy in Burkina Faso.

Method: Finger-prick blood samples of 464 children attending hospital for suspected malaria were tested for malaria by microscopy and OptiMAL-IT.

Results: The sensitivity and specificity of OptiMAL-IT were 98.7% (CI 95% = 97.6-99.8) and 96.2% (CI 95% = 94.3-98.1) respectively, with a high positive likelihood ratio (25.97).

Conclusion: OptiMAL-IT can be considered a good method to diagnose malaria in Burkina Faso, particularly in remote areas with little or no access to microscopy services.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Biomarkers / blood
  • Child, Preschool
  • Clinical Enzyme Tests / methods
  • Humans
  • Infant
  • L-Lactate Dehydrogenase / blood
  • Malaria / diagnosis*
  • Microscopy
  • Predictive Value of Tests
  • Reagent Kits, Diagnostic
  • Sensitivity and Specificity

Substances

  • Biomarkers
  • Reagent Kits, Diagnostic
  • L-Lactate Dehydrogenase