Abstract
This prospective cohort study tested whether the most common hereditary thrombophilia, factor V Leiden (FVL) mutation, is associated with nonpregnancy after IVF. Factor V Leiden mutation prevalence was very low (1.6%) and had a preliminarily positive association with pregnancy, suggesting that routine testing in a general IVF population for FVL mutation as a cause of IVF failure and infertility is not indicated.
Publication types
-
Clinical Trial
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adult
-
Cohort Studies
-
Factor V / analysis
-
Factor V / genetics
-
Factor V / physiology*
-
Female
-
Fertilization in Vitro* / methods
-
Gene Frequency
-
Genetic Testing
-
Humans
-
Infertility, Female / blood
-
Infertility, Female / diagnosis
-
Infertility, Female / genetics
-
Infertility, Female / therapy
-
Mutation, Missense / physiology
-
Pregnancy
-
Prognosis
-
Treatment Failure
-
Young Adult