Identification of LTR retrotransposons in eukaryotic genomes: supports from structure and evolution

Int J Bioinform Res Appl. 2009;5(4):365-77. doi: 10.1504/IJBRA.2009.027507.

Abstract

Ubiquitous in eukaryotes, Long Terminal Repeats (LTR) retrotransposons elements play important role in the genome evolution. Sequencing of genomes presents a great challenge of rapidly identifying them in large-scale genomic data. In this report we describe LTR_INSERT, a computational method for identifying LTR elements in genomic sequences. Our method provides structural and evolutionary supports to discover LTR elements. By applying LTR_INSERT to two rice genomes, we have identified 72 novel LTR families in the species of which LTR elements have been extensively mined.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Computational Biology / methods*
  • Eukaryotic Cells
  • Evolution, Molecular*
  • Genome*
  • Humans
  • Retroelements*
  • Terminal Repeat Sequences / genetics*

Substances

  • Retroelements