Unraveling the human embryonic stem cell phosphoproteome

Cell Stem Cell. 2009 Aug 7;5(2):126-8. doi: 10.1016/j.stem.2009.07.007.

Abstract

The human embryonic stem cell (hESC) transcriptome is well described, but minimal proteome characterization is available. In this issue of Cell Stem Cell, Brill et al. (2009) and Van Hoof et al. (2009) describe the hESC phosphoproteome and its changes upon differentiation.

Publication types

  • Comment

MeSH terms

  • Cell Differentiation*
  • Embryonic Stem Cells / metabolism*
  • Gene Expression Profiling
  • Humans
  • Phosphoproteins / metabolism*
  • Phosphorylation
  • Protein Kinases / metabolism
  • Proteome / metabolism*

Substances

  • Phosphoproteins
  • Proteome
  • Protein Kinases