Intermediate-term outcome in lung transplantation from a donor with glioblastoma multiforme

Fengshi Chen; Wojtek Karolak; Marcelo Cypel; Shaf Keshavjee; Andrew Pierre

doi:10.1016/j.healun.2009.06.022

Intermediate-term outcome in lung transplantation from a donor with glioblastoma multiforme

J Heart Lung Transplant. 2009 Oct;28(10):1116-8. doi: 10.1016/j.healun.2009.06.022.

Authors

Fengshi Chen¹, Wojtek Karolak, Marcelo Cypel, Shaf Keshavjee, Andrew Pierre

Affiliation

¹ Toronto Lung Transplant Program, Division of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

PMID: 19782299
DOI: 10.1016/j.healun.2009.06.022

Abstract

A 19-year-old man with cystic fibrosis, who was on extracorporeal membrane oxygenation, underwent bilateral lung transplantation from a donor with glioblastoma multiforme. Because the risk of tumor transmission from donor-related central nervous system malignancies remains unclear, the use of these extended donors remains controversial. In fact, there are few reports on the outcomes of lung transplantation from donors with central nervous system malignancy. This patient was critically ill with extracorporeal membrane oxygenation support before transplantation, but is well without any sign of malignancy 20 months after transplantation.

Publication types

Case Reports

MeSH terms

Adult
Brain Neoplasms*
Cystic Fibrosis / surgery*
Glioblastoma*
Humans
Lung Diseases / surgery*
Lung Transplantation*
Male
Risk Factors
Tissue Donors*
Treatment Outcome